Emmett Schmidt

Emmett Schmidt

Company: Merck & Co

Job title: Vice President, Lead External Collaborations Project Team Global Clinical Development

Seminars:

Synergy is a 4 Letter Word: Lessons of Independent Action as an Explanation for the Efficacy of Cancer Clinical Combination Therapies 4:00 pm

– Immuno oncology drugs are failing at an unprecedented rate, perhaps because too much reliance has been placed on pre-clinical thinking about synergy – Based on the mathematics of Independent Action, synergy has not been seen in any immuno oncology registration trials to date – To progress development of combinations of ADC and PD-1 immune…Read more

day: Day One

Panel Discussion: Exploring the Strategic Challenges of Moving Forward a Drug You Want to Combine with PD-1 in Chemo+PD-1 Progressors 12:30 pm

Understanding the different current comparators and benchmarks Exploring the differences in PD-1 naïve and PD-1 progressors Dissecting why sometimes beating chemo and PD-1 could be an unachievable bar Discussing whether with late-line in-effectivity, how you know it won’t work in early line? Considering the health authorities’ standards on the matterRead more

day: Day One

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